خلاصه داستان : بتهوون، سگ سنت برنارد، پدر می شود، اما عشقش میسی به دام می افتد و توله هایش نیز در خطر همان سرنوشت قرار می گیرند...

Beethoven is back -- and this time, he has a whole brood with him now that he's met his canine match, Missy, and fathered a family. The only problem is that Missy's owner, Regina, wants to sell the puppies and tear the clan apart. It's up to Beethoven and the Newton kids to save the day and keep everyone together.

خلاصه داستان : یک سنت برنارد غرق در مرکز توجه خانواده ای عاشقانه می شود ، اما باید با دامپزشکی که در حال خوابیدن برای سگ است و حامیانش مبارزه کند.

The Newton family live in their comfortable home, but there seems to something missing. This "hole" is filled by a small puppy, who walks into their home and their lives. Beethoven, as he is named, grows into a giant of a dog... a St Bernard. Doctor Varnick, the local vet has a secret and horrible sideline, which requires lots of dogs for experiments. Beethoven is on the bad doctor's list.